Pharmaceutical and Analytical study of Yashtimadhu Anjana prepared with various wick materials using FTIR And XRD.
DOI:
https://doi.org/10.70066/jahm.v14i4.2616Keywords:
Collyrium, FT-IR (Fourier Transform Infrared Spectroscopy), Glycyrrhiza glabra, soot, XRD (Powder X-ray Diffraction).Abstract
Background: Conversion of herbal drugs in soot/carbon can be done and brought in therapeutic practice. Based on this innovative concept, Yashtimadhu Anjana was prepared with 3 different techniques. Aim: Pharmaceutical and analytical characterisation of end product studied for concluding suitable material for soot preparation. Objective: To evaluate pharmaceutical and analytical characterization of 3 different methods of preparation of Yashtimadhu Anjana and conclude the suitable material for soot preparation Material and Methods: For soot preparation 3 substrates were used viz. cotton cloth, surgical cotton and surgical gauze. Precise weighing was done for unbleached standardized cotton cloth (20 cm²). After that, identical masses of surgical gauze and surgical cotton wick were made for comparison. All 3 wicks soaked with GG (Glycyrrhiza glabra) decoction and dried for 7 times & burnt in cow ghee to create black soot. Obtained product subjected for pharmaceutical and analytical analysis according to the Ayurvedic Pharmacopoeia of India. Results: Soot obtained from cotton cloth 10.23gms, surgical cotton 12.89gms and surgical gauze 9.18gms. FT-IR of cotton cloth showed minor specific bands which may be due to environmental exposure or surface impurities. Surgical cotton soot showed minor chemical modifications which may occurred during processing. Whereas surgical gauze does not show any distinct peaks and closely resembles that of purified cellulose. XRD analysis verified, all soot samples were primarily amorphous carbon. Conclusion: Though cotton cloth and surgical cotton produced more soot however surgical gauze may be appropriate for therapeutic purposes. Despite lower yield, surgical gauze may be determined to be suitable substrate because of relatively cleaner spectral profile as per FTIR findings, and all three soot are basically amorphous in nature which was confirmed by XRD analysis.
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