Journal of Ayurveda and Holistic Medicine (JAHM)

Therapeutic Potential of Chamomile in Women’s Health and Wellbeing: A Narrative Review

D Saravanan — 2026-06-22

Background: Chamomile, derived from both Matricaria chamomilla and Chamaemelum nobile (L.) All, has long been used as a holistic treatment and has demonstrated the ability to address health issues associated with women's health, including menstrual cramps, anxiety, stress, and sleep problems. Chamomile has three major active compounds – apigenin, alpha bisabolol and chamazulene – which provide anti-inflammatory, analgesic, antispasmodic and mild sedative properties. Chamomile has an apple-like fragrance, which promotes relaxation through aromatherapy. Objectives: The purpose is to review the effectiveness of chamomile in relieving the symptoms of dysmenorrhea, anxiety, and sleep disturbances in women (e.g., premenstrual syndrome, menopause, postpartum) relative to peppermint and lavender. Methods: The review is based on a review of a comparative analysis of the above-mentioned herbs. This narrative review explains and critically evaluates reported experimental and clinical studies on the role of chamomile in women’s health. Results: Reported studies support the effectiveness of chamomile in reducing menstrual pain, promoting calming through aroma, and reducing anxiety while improving the quality of life associated with multiple women's health conditions. In addition, it has unique categories of benefits. Conclusion: Despite the challenges of small sample sizes, varied dosages and inconsistent preparation techniques, chamomile demonstrates strong potential as a gentle, sensory alternative therapy. Future studies should emphasize the need for standardized studies with larger samples, longer follow-up and optimized aromatherapy techniques to assess the long-term safety of chamomile

Exploring the Physiology of Folliculogenesis through the Lens of Ayurveda: A Narrative Review

Chesta Chesta — 2026-06-22

Background: Folliculogenesis is a highly regulated physiological process involving the growth and maturation of ovarian follicles, governed by endocrine, paracrine, and autocrine mechanisms. Hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), and Anti-Mullerian hormone (AMH) play an important role in follicular recruitment, growth, and ovulation. In the current era, increasing reproductive disorders highlight the need for an integrative understanding of ovarian physiology. Objective: The objective of this review article is to analyse folliculogenesis and to interpret its physiological mechanisms through the principles of Ayurveda by correlating them with modern reproductive science. Materials and Methods: This is a narrative review, critically analyzed and compiled the literature related to folliculogenesis and female reproductive physiology from classical Ayurvedic texts and contemporary biomedical literature. Keywords such as folliculogenesis, AMH, FSH, LH, and Artava were used for literature search. Results: Folliculogenesis involves gonadotropin-independent and dependent phases regulated by AMH, FSH, and LH. These processes can be interpreted in Ayurveda through the functional role of Dosha, where Kapha governs growth and preservation, Pitta regulates metabolic transformation, and Vata facilitates ovulation. The associated mechanisms and clinical relevance are discussed. Conclusion: Ayurveda provides a holistic approach to understanding folliculogenesis by integrating systemic and local ovarian functions. This perspective may help in better understanding reproductive physiology and its disorders.

Phytochemical Fingerprinting of Polyherbal Oil and Its Topical Derivatives (Gel and Ointment) using LC-MS analysis.

Surekha S Medikeri — 2026-06-22

Background: Polyherbal formulations play a pivotal role in Ayurveda therapeutics; while their complex phytochemical composition demands analytical validation for their quality and safety. Pharmaceutical development of classical Ayurveda formulations to advanced dosage forms is the dire need for enhanced patient compliance. Aim: To develop a polyherbal oil and its topical derivatives (gel and ointment) and comparatively characterize their phytochemical fingerprints using LC–MS analysis. Methods: The Polyherbal oil was prepared by following the basic principles of Sneha kalpana(oil and ghee preparations) and its conversion to gel and ointment were done by the contemporary principles and their comparative analytical evaluation is carried out using Liquid Chromatography–Mass Spectrometry (LC-MS) under identical chromatographic conditions. Results: LC-MS analysis revealed the presence of flavonoids, terpenoids, phenolic glycosides, sterols, and fatty acids across all formulations. Polyherbal oil demonstrated broader phytochemical diversity with compounds such as α-pinene, harmol, curdione, campesterol, and lupeol, while the ointment and gel retained selective phytoconstituents including glyasperine D, syringing, homoorientin, lupeol derivatives, flavonoids glycosides, and isoflavonoids. Comparative analysis showed partial retention of key phytochemical groups despite formulation modifications. Conclusion: The study demonstrated retention of major phytochemical groups across all formulation dependent variations in LC-MS profiles. LC-MS fingerprinting was found useful for comparative phytochemical evaluation of topical dosage forms.

Identification of a Non-Cannabinoid Lipid–Sterol Chemotype in Cannabis sativa Roots using SCFE–GC–MS Analysis

Hemanth Kumar Manikyam — 2026-06-22

Background: Cannabis sativa roots remain comparatively underexplored despite historical medicinal use and emerging reports of bioactive sterols and lipid-derived constituents. Previous phytochemical investigations have focused predominantly on aerial plant parts and cannabinoids. Aim: To characterize the phytochemical profile of Cannabis sativa root extract obtained through supercritical CO2 extraction using GC–MS analysis and to identify the dominant chemical classes present in the extract. Methods: Authenticated Cannabis sativa roots collected from Haridwar, Uttarakhand, India, were shade dried, processed, and extracted using supercritical CO2 extraction at 250 bar and 45°C with methanol as co-solvent (10%). GC–MS analysis was performed using a Shimadzu Nexis GC-2030 coupled with GCMS-QP mass spectrometer fitted with an Rxi-5Sil MS capillary column. Compound identification was based on retention characteristics and spectral matching with standard libraries. Triplicate injections were used for repeatability assessment. Results: The extract demonstrated a lipid- and sterol-rich composition dominated by n-hexadecanoic acid (16.69%), γ-sitosterol (13.26%), palmitic acid glyceride (11.73%), octadecadienoic acid derivatives, linolenic acid derivatives, campesterol, and stigmasterol. Only trace cannabinoid-related signals were observed. The detected profile was characterized primarily by fatty acids, glycerol esters, phytosterols, and related metabolites. Conclusion: Cannabis sativa roots possess a distinct non-cannabinoid phytochemical profile enriched in fatty acids, glycerol esters, and phytosterols. The findings support further phytochemical and pharmacological investigation of Cannabis roots using validated analytical and biological methods.

Analytical Phytochemical Fingerprinting of Durva Taila (Cynodon dactylon (L.) Pers.) Using Gas Chromatography–Mass Spectrometry (GC–MS): Insights into Potential Wound-Healing Bioactive Constituents

Tarun Pawar — 2026-06-22

Background: Durva Taila is a formulation which is described in classics for the management of wounds, bleeding, and inflammation. It is being used till now for the treatment of various diseases. As per the classics, sesame oil has to be used in the preparation of Durva Taila but in the present analytical study coconut oil is used as base because it has Madhura rasa and sheeta virya which could have better effects in wound healing. As this formulation lacks a systematic analysis of its chemical composition so by using modern analysis methods, we can provide its true potential in wound care and attain the greater acceptance of this Ayurvedic formulation.

Materials & Methods: A 100ml sample of Durva Taila was prepared, with slight change choosing coconut oil as base instead of Sesame oil, following classical Ayurvedic procedures. Under standard protocols, GC-MS analysis was carried out to recognize volatile and semi-volatile phytoconstituents present in the formulation.

Results & Discussion: The GC-MS analysis revealed a complex mixture of compounds including fatty acid esters, hydrocarbons, aldehydes & phytosterols derivatives. Total 26 key bioactive molecules at different retention time were identified which included 2-Heptanone,2-decenal,(E)-, Glycidyl palmitoleate, Dodecanoic acid (lauric acid), Pentadecanoic acid, δ-dodecalactone, 9-Octadecenamide, (Z)-, Pinoresinol, dimethyl ether (also known as (+)-eudesmin), etc. which are well established for their anti-inflammatory, anti-nociceptive/analgesic, anti-microbial, anti-oxidant, tissue repairment and regenerative properties. The presence of these multiple bioactive phytoconstituents suggests a cumulative synergistic mechanism underlying the therapeutic effects of Durva Taila.

Conclusion: The isolation and identification of these bioactive compounds provides strong scientific evidence supporting the use of Durva Taila in wound healing and inflammation- analgesia management. This further encourages pharmacological and clinical studies in vivo and human trials to validate its potency and delve into potential integration to modern therapeutics.

Hrudaya Marma and Dasha Dhamani in Relation to Contemporary Cardiovascular Anatomy: A Narrative Mini Review of Sinotubular Junction Diameter Variations

Pradeepkumar G Akki — 2026-06-22

Background: In classical Ayurveda literature, the Hrudaya (heart) is conceptualized as a supreme vital node, designated as a Sadhya Pranahara Marma (vital anatomical point causing sudden death upon injury). It is intricately connected to the Dasha Dhamani (ten great vessels). While the functional anatomy has been explored, the specific metrological and structural correlations of the proximal great vessels—particularly the ascending aorta and its sinotubular junction (STJ)—remain underexplored in integrative medicine. Objectives: To critically analyze classical Ayurveda concepts of Hrudaya Marma and Dasha Dhamani, correlating them with the contemporary anatomy and clinical pathology of the aortic root, STJ, and ascending aorta. Material & Methods: A comprehensive narrative review was conducted using classical Ayurveda texts, authoritative commentaries (e.g., Pratyaksha Shareera), and contemporary cardiothoracic, embryological, and imaging literature sourced from major electronic databases. Results: Textual measurements of the Aarohini Mahadhamani (ascending great vessel)—documented as two Angula (fingerbreadths) in length and five Angula in circumference—correspond with striking precision to the human ascending aorta. Its three Kotara (alcoves/pockets) represent the aortic sinuses. Furthermore, contemporary observational evidence indicates that the STJ diameter, particularly when indexed to body surface area, is an independent predictor of acute type A aortic dissection. Conclusion: Correlating the ancient metrological framework of Hrudaya Marma with modern STJ and aortic root paradigms validates traditional Ayurveda quantitative anatomy. This synthesis provides a robust translational framework for preventive cardiology, emergency medicine, and forensic analysis.

Prof. Dr. Paneenazhikath Narayana Vasudeva Kurup: Frontiersman of Ayurveda

Shivshankar Rajput — 2026-06-22

The Globalization of Ayurvedic practice has gained momentum over the past three decades, largely driven by personalities associated with Ayurveda, such as Prof. Dr. Paneenazhikath Narayana Vasudeva Kurup (Dr. P.N.V. KURUP). He is an expert in Ayurveda and has been instrumental in promoting, propagating, and elevating its status nationally and internationally. He has published several articles and a book, A Handbook of Indian Medicinal Plants, on the traditional Indian Medicine System. His pivotal role in integrating Ayurveda with contemporary scientific paradigms, particularly in analysis and advancement, is highly regarded in Panchakarma and throughout Ayurveda. He was the key person who fully understood the importance of post-graduation courses in Ayurveda and served as the teacher for the first batch of post-graduation courses in Gujarat Ayurved University (GAU), Jamnagar. He was the frontierman in the globalization of Ayurveda at the international level, and for this, he understood the importance of English translation of Ayurveda books. He also established the Indian Institute of Ayurvedic Pharmaceutical Sciences at GAU, Jamnagar, and served as the only Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homeopathy (AYUSH) Commissioner of Ayurveda. The present study unfolds Dr. P.N.V. Kurup’s scientific accomplishments, advances in the literature, and the resolution of scientific quandaries under his mentorship, as well as his professional journey, research publications, and the array of awards and recognitions received.

Ayurvedic Intervention in Pediatric Sensorineural Hearing Loss (Badhirya): A Case Report

Vimal M Mistry — 2026-06-22

Background: Sensorineural hearing loss (SNHL) is a type of hearing impairment typically associated with aging, where the pathology lies in the inner ear or the vestibulocochlear nerve. It might be congenital or acquired. Pediatric SNHL is comparatively rare, and even more so when linked to allergic etiologies. Hearing loss is associated with Badhriya (~deafness) in Ayurveda and one among the Karnaroga. Clinical findings: This case describes 15year old girl presented with symptoms such as partial hearing loss, tinnitus and ear pain over a period of 5 months. The underlying etiology was associated with Allergic Rhinitis, a rare but clinically significant contributor to SNHL in children. She was diagnosed with SNHL in March, 2025. Interventions: Ayurvedic treatment commenced with procedures viz Nasya (~nasal therapy), Karnapoorana (~auricular oil therapy), Matrabasti (~oil enema) are given for 23 days and Ayurvedic medicaments viz Pathyadi Kvatha, Triphala Guggulu and Sudarshan Ghanvati for 23 days and follow up medicaments for 28 days. Outcome: Pure tone Audiometry (PTA) showed significant improvement in hearing threshold. The right ear improved from a mean of 33 dB (mild hearing loss) to 17.5 (Normal sensitivity) dB indicating approximately 46.9% improvement. The left ear improved from a mean of 80 dB (severe hearing loss) to 22.5 dB (mild hearing loss), showing approximately 71.8 % improvement. Symptomatic relief was evident, with tinnitus reduced from 6 to 2 and ear pain score reduced from 7 to 3 on the Visual Analogue Scale (VAS). Conclusion: This case highlights rare association of pediatric SNHL with allergic rhinitis and demonstrates that individualized Ayurvedic management, including therapeutic procedures and medications leads to clinical and audiometric improvement. Improvements were supported by clinical findings and PTA reports with sustained benefits and no adverse effects observed during treatment and follow up.

Multimodal Ayurvedic approach in the management of Sirajanya Dushtavrana (Chronic venous Ulcer): A Case Report

S R Sreechand — 2026-06-22

Background: Chronic venous ulcers are caused by valvular incompetence and are considered as serious complication of chronic venous insufficiency (CVI) which can lead to cellulitis, infections, osteomyelitis and eventually require amputation. Ulcer (Vrana) in Ayurveda has been explained in detail by Acharya Susruta. In this case, it denotes chronicity, painful), discharge, and is associated with venous system, etc. were suggestive of sirajanya dushtavrana (chronic venous ulcer). Ayurvedic interventions focused on shodhana and ropana therapies. Clinical findings: A 61-year-old non diabetic female presented with chief complaints of a non-healing ulcer of size 15X8X0.5 cm with pain and discharge above the medial malleolus of the right lower limb, and was diagnosed as sirajanya dushtavrana. She had the same history two years back and had taken treatment, but the condition persisted with delayed healing. Intervention: Treatment initiated with rookshana karma (dry inducing therapy) and Deepana (Digestion stimulating) medicines, snehapana (internal oil therapy) virechana (purgation therapy) followed by basti (medicated enema) and Vrana Basti were adopted along with proper wound care and internal medications. Outcomes: Wound healed completely with tissue epithelialization, scar formation and significant reduction in pain was achieved without any complications, in duration of 30 days of treatment, and 5 months of follow-ups. Follow-up was uneventful. Conclusion: This case demonstrates successful management of chronic venous ulcer of size 15x8x0.5 cm is completely healed and change of VAS from 6 to 0. using a multimodal ayurvedic approach, including classical snehapana, virechana, basti, Vrana Basti and internal medications. Treatment duration was approximately 30 days and 5 follow-ups were done in every month, with no adverse effects and recurrence. Complete healing was achieved in 6 months. This case suggests the efficacy of holistic ayurvedic therapies and proper wound care in the management of long-standing venous ulcers.

Ayurvedic management of chronic non-healing venous leg ulcers in a patient with diabetes mellitus: A case report

Sree R Nair — 2026-06-22

Background: Chronic venous insufficiency (CVI) and varicose veins are considered to be the contributing factors for the onset of Venous leg ulcer. Venous Leg Ulcers remain one among the frequently reported cases in the daily life clinical practice. The ulcers having pain, edema, itching, and discharge make it difficult for the patient to carry out his day-to-day activities. It affects the quality of life of the patient thus tarnishing both his physical and mental well-being. Venous ulcers are correlated with Dusta vrana in Ayurveda because of its typical nature described in Ayurveda classics. If intertwined with other contributing factors like Diabetes Mellitus, it can either aggravate the ulcer or prevent the healing process even after administration of medications. Clinical Findings: The present case report, documents the efficacy of treatment protocol derived from the Ayurveda texts in managing two non-healing Venous ulcers in a known case of Diabetes Mellitus. The patient had severe pain, discharge and itching along with the discoloration of left lower limb. Intervention: Internal administration in the form of Sahacaradi Kashaya, Majistadi kashaya, kaishora guggulu, Triphala guggulu along with external application of Triphala masi found to be effective in healing of both ulcers. Outcome: The patient was reviewed at two-week intervals. Gradual reduction in ulcer dimensions, pain, discharge, and surrounding pigmentation was observed. Pain scores improved by the end of treatment (from VAS 8 to Vas 0). Complete epithelialization of both ulcers was achieved in three months. Conclusion: Proper treatment along with diet to keep the blood sugar levels under control and regimens like foot end elevation, bicycling exercise to improve the venous drainage of lower limb have helped the patient to recover from his illness and in improving his quality of life after the completion of treatment.

Integrated Ayurvedic Approach to Managing Generalized Anxiety Disorder through Yukti Vyapashraya and Sattvavajaya Chikitsa: A Case Report

Rajimunnisa Begam Shaik — 2026-06-22

Background: Generalized Anxiety Disorder is a common mental health condition characterized by persistent and excessive worry, restlessness, irritability, fatigue, difficulty concentrating, muscle tension, disturbed sleep, and impaired daily functioning. In Ayurveda, these symptoms resemble Chittodvega, caused by imbalances of the Vata and Pitta Doshas and an excess of Rajo Guna, which disrupts the Manovaha Srotas. Psychosocial stressors such as emotional neglect and interpersonal conflicts act as important nidanas in the development of the condition. Clinical findings: A 57-year-old married homemaker presented with a two-year history of persistent and excessive worry, apprehension, grief, irritability with occasional anger outbursts, emotional suppression, lethargy, disturbed sleep, and symptoms as mentioned above. Her psychosocial history included emotional dependence on her children, marital conflicts, perceived criticism, and long-term emotional suppression, which had a more impact. The Mental Status Examination revealed an anxious mood, restricted affect, psychomotor agitation, and ruminative thoughts, with preserved insight. According to the DSM-5, she was diagnosed with GAD. Intervention: The patient received a combined Ayurvedic treatment integrating Yukti Vyapashraya Chikitsa and Sattvavajaya Chikitsa. Shamana therapies included Manasamitra Vati, Vishamushti Vati, and Maha Rasnadi Kashaya, along with Panchakarma procedures such as Sarvanga Abhyanga, Swedana, Shirodhara, Shiropichu, and Basti. Sattvavajaya strategies involved Yoga Nidra, art therapy, music therapy, positive affirmations, and structured counseling for herself and her spouse. Outcomes: Marked improvements were observed in HAM-A, HAM-D, and ISI scores, decreasing from 25 to 4, 18 to 1, and 19 to 0, respectively, indicating a substantial reduction in anxiety, depression, and insomnia. Patient experienced improvement in sleep quality, emotional stability, confidence level, and QOL. Conclusion: This case illustrates that an integrated Ayurvedic approach combining Yukti Vyapashraya and Sattvavajaya Chikitsa can effectively treat Chittodvega (GAD) by balancing the tridoshas and addressing maladaptive thoughts, thereby improving psychological resilience and overall well-being.

Management of Peenasa (Chronic Rhinitis) with Ikshvaku Vamana Yoga: A Case Report

Mallika Jandara — 2026-06-22

Background: Chronic rhinitis is among the most common respiratory diseases, with allergic rhinitis affecting 20-30% of the world’s population, including India and the number of cases continuing to rise due to environmental and lifestyle changes, impacting quality of life, making it a public health issue. Peenasa, in Ayurveda has similarities to chronic rhinitis and is caused by dosha irregularities, specifically by Vata and Kapha Dosha. Clinically, Peenasa shows runny nose, nasal obstructions, sneezing, and headache. Allopathic symptomatic treatment is generally antihistamines, nasal decongestants etc. while Ayurveda focuses on the root cause removal which is done by Vamana Karma for the aggravated dosha to restore balance and prevent relapse, providing a more sustained management of the condition. Clinical Findings: A 32-year-old female with 8-years history of continuous nasal discharge-obstruction, repeated sneezing, headache, and heaviness of head, diagnosed as Kapha-predominant Peenasa; examination revealed hypertrophied turbinate and deviated nasal septum. Intervention: Vamana Karma, a Panchakarma procedure was selected as the primary intervention. Ikshvaku Phala-Ksheer Yoga was used for the procedure after which the patient was given Marichyadi Yoga as Shamana. Treatment was done for 30 days and the patient was observed over a follow-up of 2 months. Outcome: Significant improvement was observed within 45 days, with decrease in SNOT-22 score from 62 to 26 along with marked decrease in eosinophils, serum IgE and inflammatory cytokines and no adverse events were reported. Conclusion: Case shows Ikshvaku Vamana Karma followed by Marichyadi Yoga is a good approach in the management of Peenasa, as it shows relief, thereby highlighting the potential of this integrative Ayurvedic approach in the management of chronic rhinitis. Key-message & finding: Classically indicated Ikshvaku-induced Vamana with Marichyadi Yoga showed specific clinical and biomarker improvement in chronic rhinitis, suggesting its use as an Vamaka Yoga alternative to commonly used formulations for Urdhwajatrugata Vyadhis.

Holistic management of Ardhavabhedaka (migraine with aura): A case report

Ashwini G Daga — 2026-06-22

Background: Migraine is one of the most common neurovascular disabling disorders encountered in Shalakya practice. It can be defined as a paroxysmal affection with a sudden onset, usually accompanied by a severe, unilateral headache. It is a widespread, chronic, intermittently disabling disorder with or without aura. In Ayurveda, Migraine is described as Ardhavabhedaka, which is a major health issue among people in the age group 20-50 years. The attack gives warning before it strikes, black spots or a brilliant zigzag line appear before the eyes, has blurring of vision or halos around the light. This type of headache is called headache with aura. Clinical Findings: A female patient of 35 years presented with the complaints that she suddenly developed black dots, an urge to loss of vision, and then vision recovered, i.e., on and off vision block associated with recurrent attacks of headache associated with gastric disturbance. She was diagnosed with a case of Migraine with aura and was well managed with the Ayurvedic treatment modalities. Interventions: The treatment was planned after a thorough analysis of the patient based on Ayurvedic principles. Patient was subjected to Shodhana Chikitsa, Kriyakalpa procedures, Shamana Chikitsa, dietary and lifestyle modification. Outcome: Significant changes were observed in the patient, with a reduction in symptoms; the MIDAS score decreased from Grade IV (score>21) to Grade I (score 1), and visual acuity improved from 6/60 to 6/6 in the affected eye. Conclusion: This case report highlights the successful management of a chronic case with a 3-year history, which experienced significant improvement in migraine with aura symptoms over a period of 6 months with Ayurvedic treatment, including 13 days of Panchakarma and 90 days of internal medications, Yoga, and Pranayama.

Multimodal Ayurvedic Management of Obstructive sleep apnea (OSA) linked Pickwickian Syndrome (Obesity Hypoventilation Syndrome) (Sthaulya with Shwaskruchrata): A Case Report

Rohan Mohandas — 2026-06-22

Background: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder comes under purview of Obesity hypoventilation Syndrome (OHS) categorized by recurrent upper airway obstruction during sleep, resulting in snoring, excessive daytime sleepiness, fatigue, and impaired quality of life. Obesity is a major risk factor for OSA and contributes significantly to disease progression. Clinical Findings: A 38-year-old obese male (Body Mass Index (BMI) 32.5 kg/m²) presented with loud snoring, excessive daytime sleepiness, fatigue, drowsiness, disturbed sleep, recurrent upper respiratory symptoms, and progressive weight gain over six years. The patient had experienced two road traffic accidents secondary to excessive sleepiness while driving. STOP-BANG and Berlin questionnaires indicated a high risk of OSA, while the Epworth Sleepiness Scale (ESS) score was 16, suggesting excessive daytime sleepiness. Interventions: The patient underwent a multimodal Ayurvedic treatment protocol comprising Udwartana (powder scrubbing) Utsadana (oil mixed powder scrubbing) Parisheka (Pouring of Medicated decoction externally) Pradhamana Nasya with Vacha Churna (Nasal Instillation of Powder Drugs) and Lashuna Swarasa, Shadbindu Taila Nasya, Snehapana (Internal Oleation) with Panchatikta Guggulu Ghrita, Virechana (Therapeutic Purgation) internal medications (Vyoshadi Vati, Triphala Guggulu), and yoga practices including selected asanas and pranayama. Post-discharge medications and lifestyle modifications were advised. Outcome Marked improvement was observed in snoring, daytime sleepiness, fatigue and sleep quality. ESS score reduced from 16 to 0, Berlin Questionnaire categories changed from positive to negative, and STOP-BANG responses showed good clinical improvement. BMI decreased from 32.5 to 28.35 kg/m². No adverse events were reported. Conclusion This case demonstrates the potential role of a comprehensive Ayurvedic approach incorporating Panchakarma, internal medications and yoga in the management of obesity-induced OSA. Significant improvements were observed in clinical symptoms, sleep-related outcomes- Epworth Sleepiness Scale, Berlin Questionnaire Categories and body weight without any adverse effects, further large studies are warranted in order to validate this finding.

Clinical Outcomes of Ayurvedic Management in Hunter Syndrome: A Case Report

Reena Kulkarni — 2026-06-22

Introduction: Hunter Syndrome, otherwise called Mucopolysaccharidosis Type II, is a rare X- linked Lysosomal Storage disorder, occurring due to the deficiency of Iduronate-2-sulfatase enzyme (I2S). This leads to impaired Glycosaminoglycans catabolism (GAGs), resulting in the pathological accumulation of Heparan sulfate and Dermatan sulfate in multiple tissues and organs. It manifests as a progressive, multisystemic, genetic metabolic disorder. In Ayurveda, Hunter Syndrome is correlated with Sahaja Vyadhi (genetic disease) arising due to genetic defects, manifesting with persistent, impaired metabolism, coarse facies, hirsutism, multiple joint contractures, short stature, hyperactivity, and subnormal cognitive development. Methods: A single case study of a 4-year-old boy with Hunter syndrome was evaluated to analyze the efficacy of ayurvedic therapies on the quality of life. The child was managed with symptomatic treatment and rejuvenation therapy. Oral medicines were targeted for Deepana (appetite stimulant), and Pachana (digestive) to rectify metabolism and to improve cognitive abilities. Procedure-based therapies were targeted to treat physical impairments. Results: After five months of exclusive oral medications and one course of external therapies, the child showed improvement in metabolic activity, cognitive abilities and joint mobility, marking overall well-being and enhanced quality of life. Conclusion: Hunter syndrome is an early onset, progressive disorder, with high morbidity and poor life expectancy, making it a Sahaja Vata Pradhana Tridoshaja Vyadhi. Early diagnosis, genetic counseling, and an integrative approach combining contemporary and traditional therapeutic strategies may reduce mortality and improve long- term health outcomes in affected children.

Erratum

JAHM Editor — 2026-06-22

Erratum