Preliminary Physicochemical, GC–MS Characterization, Dosage and Stability assessment of Nayanasukha Rasakriya Anjana: An Exploratory Analytical Study
DOI:
https://doi.org/10.70066/jahm.v14i9.3043Keywords:
Analysis, Dosage, GC-MS, Nayasukha Rasakriya Anjana (NRA)Abstract
Background: Among Netra kriyakalpas, Anjana karma is one of the targeted therapies with wide variety of formulations indicated for different kinds of ocular pathologies. Nayanasukha Rasakriya Anjana is a modified preparation based on the classical Nayanasukha Varti Anjana. Objective: To report preliminary physicochemical, phytochemical, chromatographic, microbial-limit and accelerated-stability observations, together with exploratory dosage calculations. Methodology: A prepared Nayanasukha Rasakriya Anjana sample was subjected to the tests of organoleptic characters, pH, specific gravity, phytochemical parameters, dosage calculation, stability, chemical profiling and microbial analysis. Results: Reported measurements included pH 6.05, specific gravity 1.33, viscosity 45.65 cSt, refractive index 1.453, total phenols 0.13 mg/g and terpenoids 1.04 mg/g. TAMC and TYMC were each reported below 10 CFU/mL. GC–MS chromatogram revealed twenty-one peaks corresponding to various organic compounds. A 60-day accelerated-storage comparison was reported. Conclusion: The findings constitute preliminary analytical observations of NRA. Replication, validated sterility assurance, confirmatory chemical identification, real-time stability and ocular safety investigations are required before ophthalmic clinical use can be considered.
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