COMPARATIVE PHARMACEUTICAL STUDY OF DIFFERENT FORMULATIONS OF SHANKHPUSHPI AND MICROBIAL ANALYSIS USING GANGAJAL AND TAP WATER

Abstract

Background: The intellectual capability of children have become a matter of concern for the scientific community.
The effect of Ayurvedic drugs in improving the intellectual capacity should be subjected for a thorough analysis
which is the need of the day. Acharya Charaka has described four drugs under the heading Medhya Rasayana.
Among these, Sankhpushpi is the best and advocated in kalka form.[1] Aim: Five different dosage forms of
Sankhpushpi are prepared. Two samples of dosage forms are prepared with Tap water and Gangajal and a
comparative microbial analysis is done. (as Gangajal is known for their antimicrobial activity). Method: The dosage
forms of Sankhpushpi to be prepared are following : Sharkar, Arka, Ghanvati, Ghrit, Rasayana. The microbial
analysis are done as per standard given in Protocol for testing of Ayurvedic, Siddha and Unani Medicines.[2] Result:
Total bacterial count of the samples prepared with Gangajal is comparatively less. According to the cost syrup and
arka are the best preparation. Discussion: To make the availibilty of the drugs throughout the year, it is essential
to convert the drug into the formulation without loosing their potency. Among the five different upkalpanas of
Sankhpushpi Arka and Sharkar is cost effective. On microbial analysis the total bacterial count of the samples
prepared with Gangajal is less that proves antimicrobial property of Gangajal. Conclusion: So the study conclude
that according to the cost, syrup and arka are the best and if we prepare these with Gangajal the preparation
will have comparatively less microbial count.