Anti-Oxidant and Anti-Cancerous properties of Phanera Vahli against PC-3- In Vitro
DOI:
https://doi.org/10.70066/jahm.v12i4.1342Keywords:
Phanera vahlii, PC-3, Antioxidant, PhytochemicalAbstract
Background: Prostate cancer is the fastest-growing cancer in men, leading to mortality. Many medicinal practices are recommended for various cancers. Ayurveda and homeopathy are also contributing a lot. Plants with antioxidant properties are now being harvested by different solvents to withdraw different chemical compounds to cure prostate cancer. Objective: The purpose of the current study was to examine the anti-cancer and antioxidant properties of aqueous extract of Phanera vahli (PV) flowers against PC-3 cancer cell lines. Materials and Methods: The total phenolic content of the extract was determined by using a folin-ciocalteu reagent. The DPPH, ABTS, and H2O2 assay were used to measure the free radical scavenging activity of the PV flower extract. The MTT assay was used to evaluate the cytotoxic efficacy of the aqueous extract of the plant flowers against PC-3 at various concentrations. Results: Based on the result, the total phenolic content was present in the aqueous extract of PV flowers. Conclusion: According to the current study, PV flower extract significantly possesses antioxidant and anti-cancer properties against prostate cancer cell lines. This effect may be used in the future to the extract's ability for scavenging free radicals.
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